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Causes of Mesothelioma Other Than Asbestos

Mesothelioma is usually caused by exposure to asbestos, a class of silicate fibrous minerals. People who work with asbestos frequently develop mesothelioma following inhalation of the tiny fibres that get stuck in the lung and cause long-term damage.

However, a tiny but significant portion of mesothelioma cases are not related to asbestos. They typically occur in younger patients, or in women.

1. Viral Infections

Viruses look for a body to multiply and enter. They are tiny pieces genetic material. As opposed to bacteria, viruses are unable to live on their own and must find one to survive. Once a virus has found an appropriate host it takes over the cell's command center and makes copies of itself. The virus eventually is able to infect enough cells to cause symptoms.

Asbestos exposure causes mesothelioma when the fibers cut and cause inflammation of the thin tissue that surrounds organs. It typically develops in the lung (pleural mesothelioma), but may be affected in other parts of the chest cavity or abdominal cavity. In rare cases asbestos fibers may get into the linings of the heart and testes.

The majority of mesothelioma patients have been exposed to asbestos through their work. Construction workers, the military, and other occupations such as mechanics, shipyard workers and electricians are all at risk. The risk of exposure is also to asbestos through clothing or equipment used by relatives who work in asbestos.

There are some alternative etiologies of mesothelioma. This includes certain genetic predispositions and viruses. These are not usually considered to be significant causes of mesothelioma. In reality, the majority of mesotheliomas not associated with asbestos are purely spontaneous (idiopathic) tumors. Asbestos exposure remains the most common mesothelioma-related cause. Mesothelioma symptoms typically are not evident until 30 to 50 years after the initial asbestos exposure. In North America, most pleural mesotheliomas, and a small percentage of mesotheliomas in the peritoneal region are linked to asbestos. In Europe, the proportion of mesotheliomas that are attributed to asbestos is higher. However, it's unclear the reason for this.

2. Chemicals

Mesothelioma affects the thin layer of tissue that covers various internal organs, typically the lung lining (pleura) and, less often, the abdomen's lining (peritoneum). The exposure to asbestos is the most frequent cause of mesothelioma. Other causes are possible, but they are not generally considered to be significant factors in developing this rare cancer.

Asbestos is one of the minerals that are made up of microscopic fibers that were extensively used in construction before being snubbed for safety reasons in late 1970s. Exposure to asbestos can occur through water, air or food. The most susceptible to asbestos exposure are miners, shipyard and other tradespeople in the construction industry, contractors, remodelers and asbestos manufacturers.

When asbestos fibers are inhaled they can irritate the lung's lining (pleura) or more frequently, the abdomen's lining (peritoneum). The irritation can last for a long time and eventually cause DNA damage in the cells, which later develop into mesothelioma cancers.

Mesothelioma is usually diagnosed in people who have been exposed to asbestos while working. The most likely to be exposed are those working in construction and manufacturing jobs that require asbestos, such as asbestos installers or roofers. Shipyard workers, veterans of the military and those working on or off naval vessels, or at military bases could have also been exposed to asbestos.

The mesothelioma symptoms are not well-studied and can be a resemblance to other conditions, so it is essential to consult your doctor if you have any symptoms or signs of this rare disease. If your doctor suspects that you are suffering from mesothelioma, they will refer you to a specialist to conduct further tests.

3. Genetics

Most often asbestos exposure is the primary reason for mesothelioma. It usually happens in the workplace. It is also associated to other mineral exposures, such as silica or erionite. The signs of mesothelioma could be noticed between 20 and 60 year after the initial exposure.

When exposed to asbestos, the needle-like fibers may cause irritation to the lining of the lungs (pleura). This can result in an accumulation of fluid in the lungs, which triggers the onset of mesothelioma. The mesothelioma is a cancer caused by what tumor cells are typically malignant. They can cause breathlessness and chest pain, and weight loss.

Cancers arise when a sequence of genetic changes (mutations) happen in the cell DNA, which normally tells the cells how to grow and behave. The cells that have been altered begin to multiply out of control and form tumors. The cancerous cells in the process invade and destroy healthy organs and tissues. Mesothelioma is not an exception.

Researchers aren't able to determine the mesothelioma's exact cause, however, they have theories. One theory is that asbestos-related mutations in DNA occur because of certain chemicals or radiations that are used in the production of asbestos-related products. Another theory is that asbestos-related mutations are caused by the presence of the virus SV40 in the bloodstream of those who work with asbestos.

It is important to discuss any past asbestos exposure with mesothelioma specialists. Asbestos-related mesothelioma could have symptoms that are similar to other diseases or conditions. This makes it difficult for general oncologists to identify this particular type of cancer. Specialists in mesothelioma can carry out specific tests to identify this type of cancer. For instance mesothelioma specialists may use imaging scans to determine if the cancer has spread and what causes pleural mesothelioma type it is.

4. Alcohol

Mesothelioma, a type of cancer, is found in the tissues that surround certain organs. The most frequent mesothelioma form affects the lining of the lungs (pleura). Other types of mesothelioma occur in the lining of the abdomen or the heart. Mesothelioma also occurs in the testicles (mesothelioma of the tunica vaginalis).

People are most at risk of developing mesothelioma because of asbestos exposure at work. Asbestos fibres can float for long periods of time in the air, making it easy to breathe in and consume. These fibers can irritate organ linings, and cause DNA mutations, leading to tumors.

The symptoms of mesothelioma typically are not evident until 20 to 60 years after the initial exposure. Often, symptoms such a shortness of breath or chest pain can be mistaken for Causes of Mesothelioma Other Than Asbestos other ailments. General oncologists often misdiagnose mesothelioma owing to their lack of knowledge about the disease and its distinctive symptoms. Patients should ask for an appointment with mesothelioma specialists in order to ensure they receive the best possible treatment.

Asbestos exposure is the sole known cause of mesothelioma. Asbestos is a naturally occurring mineral, was used in the past for insulation, fireproofing, and other reasons. Workers in factories that used asbestos were subjected to dust and fibers while during their work. Plumbers and electricians were among those who were exposed, along with factory workers, painters shipyard employees, construction crews and veterans.

Exposure to asbestos at work occurs most often when a person brings asbestos fibers home from their workplace on their clothing, skin, or hair. Families of workers who were exposed to asbestos are at risk of developing mesothelioma too. Mesothelioma patients have been told that their families have felt a general sense of being sick or mesothelioma-related symptoms such as shortness of breath, a buildup of fluid in the lungs (pleural effusion) and swelling of the scrotum (hydrocele).

5. Smoking

Many people exposed to asbestos do not develop mesothelioma, which suggests that there are other factors at play. A person may be more susceptible to mesothelioma, as an example, if they have a genetic predisposition to cancer or any other condition that increase the risk of mesothelioma. Other causes of mesothelioma can be exposure to other harmful substances such as radiation and chemicals and being exposed to viral infections. Mesothelioma is also caused by the mutation of the gene. However this is mesothelioma caused by asbestos a less frequent cause.

The symptoms of mesothelioma can be similar to those of other diseases and disorders which makes it difficult for doctors to identify the disease. Because of this, mesothelioma can be incorrectly diagnosed. The only way to confirm a mesothelioma diagnosis is to take biopsy.

Asbestos fibers can cause irritation when inhaled and can travel through the pleura (the lung's lining). This irritation can lead abnormal cancer cells to grow in the pleura. If the tumors expand they may enlarge the lung tissue and cause pain and other symptoms such as breathlessness or breathing difficulties.

If you or a loved one has been diagnosed with mesothelioma it is important to see a specialist right away. They can assist in determining whether the symptoms of mesothelioma caused by asbestos are related to mesothelioma, or other ailments. They may also recommend tests to determine the presence of cancerous cell. These include chest Xrays, CT scans or MRIs and blood tests. They can also recommend you to a specialist in mesothelioma treatment. The specialized mesothelioma treatments available can significantly improve the outlook for patients. However, the best approach to treatment will depend on the pericardial mesothelioma causes type.